Background:
@EN Electroconvulsive therapy (ECT) can produce dangerous complications, such as arrhythmias, transient hypertension, and increases in intraocular pressure. This study was designed to whether propofol, in comparision with thiopental, would
attenuate
these hypertensive responses and increases in intraocular pressure.
@ES Methods:
@EN Twenty patients were studied during courses of ECT administration, each patient receiving propofol or thiopental on different occasions. The induction dose was 1.6mg/kg of propofol and 3mg/kg of thiopental so. Mean arterial pressure, heart
rate,
rhythm and intraocular pressure were checked before induction (control), after administration of succinylcholine, immediately, 5 min, and 10 min after ECT administration. Recovery time was also compared between two groups.
@ES Results:
@EN Mean arterial pressure was lower following propofol than thiopental(p<0.05) immediately after ECT. Heart rate was lower following propofol than thiopental (p<0.05) immediately, 5 min, and 10 min after ECT. Cardiac rhythm abnormalities were
infrequent and not serious. Intraocular pressure was lower following propofol than thiopental(p<0.05) immediately, 5 min, and 10 min after ECT. Recovery time of propofol (6.5±0.8min) was shorter than thiopental(7.5±0.9 min).
@ES Conclusions:
@EN Propofor for ECT induction would seem to be an ideal drug, as it attenuates hypertensive responses and increases in intraocular pressure. (Korean J Anesthesiol 1996;30: 305~310
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